Enable or Disable Possibly Unwanted Applications Protection contains registry files that can quickly enable or disable "Possibly Unwanted Applications Protection" in Windows Defender as explained in this guide.
While you can edit the registry, this download simplifies that task.
The Potentially Unwanted Applications (PUA) protection feature in Windows Defender Antivirus can identify and block PUAs from downloading and installing on endpoints in your network. These applications are not considered viruses, malware, or other types of threats, but might perform actions on endpoints that adversely affect their performance or use.
There is a third option that can notify you, but not block downloads. Details, once again, can be found in this guide.