Contig is a single-file defragmenter that attempts to make files contiguous on a disk. It's perfect for quickly optimizing files that continuously become fragmented or that you want to ensure are in as few fragments as possible.
There are several NT disk defraggers on the market, including Winternals Defrag Manager. These tools help perform general defragmentation of disks, but while most files are defragmented on drives processed by these utilities, some may not be. In addition, it is difficult to ensure that particular files that are frequently used are defragmented - they may remain fragmented for reasons specific to the defragmentation algorithms used by the defragging product that has been applied. Finally, even if all files have been defragmented, subsequent changes to critical files could cause them to become fragmented. Only by running an entire defrag operation can one hope that they might be defragmented again.
Use Defraggler to defrag your entire hard drive, or individual files - unique in the industry. This compact and Windows application will fully support NTFS and FAT32 file systems. Portable version available.