VIPRE Rescue works as a portable executable by extracting all of the files automatically to C:\VIPRERESCUE and automatically begins scanning. You can choose a custom folder before extracting the files.
Scanning takes some time, but that's very common with similar apps considering Windows has tens of thousands of files.
Without being infected, we can't be sure how effective VIPRE Rescue is, but we would keep this in our toolbox as a tech. We've had positive reports of success on our Facebook page. The definition files frequently update, so bookmark this page to download the latest version when you need it.
Consider using Malwarebytes for complete antivirus protection and to protect your devices, data, and privacy.