Avast! Virus Definitions allow you to update your Avast anti-virus versions offline manually.

AVG Anti-Virus Update allows you to manually update your AVG when the automatic update fails. Download the latest AVG Free Edition here. Video tutorial available.

Avira Antivir Virus Definition File Update, or the Fusebundle Generator, allows you to update your Avira products by downloading all the definitions or incrementally, so you always have the latest definitions.

Beyta Offline Update is a free and portable downloader app that allows the downloading of needed Antivirus and antimalware offline updates.

Bitdefender's latest virus definitions.

ClamWin Free Antivirus Definition Files will update your ClamWin Free Antivirus antivirus when the auto-update fails, or you need to update another PC without internet access.

Comodo Anti-Malware Database updates Comodo Antivirus or Internet Security when the auto-update fails or you need to update another PC without internet access.

eScan Weekly Offline Updates can update your MicroWorld Technologies eScan, MailScan, eConceal, WebScan, and X-Spam products offline when there's no internet connection available.

F-Secure Virus Definitions provides you with the latest virus definitions for F-Secure Anti-Virus 5 and F-Secure Anti-Virus 4.

IKARUS Security Software Virus Database gives you the latest database for IKARUS if the regular update fails or for updating offline.

K7 DSM Fixer can fix corrupted K7 antivirus signature database files.

K7 Offline Updater can update your K7 antivirus signature database without an active internet connection.

Kaspersky Update Utility is a freeware app for downloading updates for any installed Kaspersky Lab products.

McAfee DAT File contains up-to-date virus signatures and other information for McAfee products.

Microsoft Security Essentials Definition Updates downloads and installs the latest Microsoft Security Essentials for Windows definition updates.

Norton Virus Definitions for Norton AntiVirus, Norton Internet Security, 360, Endpoint Protection, and Mail Security will ensure your Norton AntiVirus product contains the most up-to-date detection and prevention.

Quick Heal Offline Product Updates can update all Quick Heal products when you need to update offline, or automatic updates fail.

REVE Virus Signature Updates can be used to update REVE Antivirus, Internet Security and Total Security to the latest virus definitions.

Trend Micro Pattern File for Windows is the Official Pattern Release or OPR for Trend Micro's latest compilation of patterns for identified viruses.

VIPRE Definitions will update your VIPRE antivirus when the auto-update fails, or you need to update another PC without internet access.

Windows Defender Definition Updates for timely updating of your Windows Defender if the automatic update happens to fail.

Zillya! Antivirus Definition Updates are the virus signatures for Zillya! Antivirus and Zillya! Internet Security for use if the auto-update fails or you are offline.